Sincetreating HCC cells for 24 or 48 hours with IFN-α slightly increasedthe expression of STAT1 and had no obvious effects on SOCS1 expression, whichwas similar to the patterns seen in the normal liver cell line L02, we chose touse the IFN-α treatments for 24 and 48 hours as the background to seethe effect of combinations with the virus. Here, SOCS1 is linked to hepatocellular carcinoma.