GJB2 and sensorineural hearing loss disorder: We performed a comprehensive analysis of GJB2 and GJB6 in 53 non-syndromic patients and scanned the whole mitochondrial genome for mutations in a cohort of 95 paediatric Portuguese SNHL patients recruited in a hearing clinic to investigate the relative contribution of common genetic etiologies to their disorder, provide effective assessment of genetic risk, and to better counsel their relatives.