TGIF1 and Abnormal intestine morphology: To prove the involvement of TGIF1 in radiation-induced intestinal damage, we followed the survival of TGIF1 deficient mice under two irradiation conditions: a radiation–induced lethal gastrointestinal syndrome after 13 Gy total body irradiation (TBI), and localized radiation-induced enteropathy after 19 Gy irradiation.