EIF2AK2 and retinal ischemia: Moreover, it has been suggested that LB polysaccharides (LBPs) effectively protected the retina from neuronal death and apoptosis by inhibiting proapoptotic signaling pathways, such as c-Jun N-terminal protein kinase (JNK), dsRNA-dependent protein kinase (PKR), and caspase-3 activity in retinal ischemia/reperfusion injury, confirming a neuroprotective role in ocular diseases [56].