There was a significant association between LCN2 staining and VEGF-A expression (p = 0.021), whereas LCN2 showed no significant associations with other angiogenesis markers such as vascular proliferation index, glomeruloid microvascular proliferation, VEGF-C, VEGF-D and bFGF2 expression, nor with vascular invasion of tumor cells (in lymphatic or blood vessels). This evidence concerns the gene VEGFC and neoplasm.