Although altered expression of transcripts encoding presynaptic secretory machinery including SYN2, NSF, synaptotagmin, synaptobrevin, synaptophysin, SNAP25, and RIMS have been reported in various brain regions such as PFC, STG, and amygdala [7], [15], [22], [50], our study is first to link this mechanism to a comprehensive panel of genes focused on the function of SNARE complex in the temporal cortex in schizophrenia. The gene discussed is SYN2; the disease is schizophrenia.