In contrast, samples from the autophagic myopathy group showed moderate to frequent LC3- and p62-positive fibers characterized by coarsely punctate staining pattern (Figs. 2G and 2I) that tended to coalesce, resulting in zones of increased staining running linearly along the longitudinal axis of the fiber and most commonly located in the fiber center (Figs. 2E and 2F). Here, SQSTM1 is linked to myopathy.