Regarding the selected genes in other CNA/UPD areas, the AKT3/PIK3CA pathway [42], [43], the KRAS/RAP1B/RAP1GAP/BRAF pathway [44], [45], and the VEGFC pathway [46], [47] have been known to participate in thyroid carcinogenesis/cancer progression. The gene discussed is RAP1GAP; the disease is cancer.