To date, although several possible markers for HCSCs, including CD133 [22], [58]–[61], EpCAM [8], [21], [62], CD90/CD44 [61], DLK [63], CD24 [62], [64], CD13 [65] and OV6 [66], have been used to isolate putative CSCs from HCC in different studies, it is unknown which of these may be a “one-fits-all” marker for CSCs in HCC. The gene discussed is EPCAM; the disease is hepatocellular carcinoma.