In addition, there was no correlation between SMN2 copy number and MHFMS score in Type II or III SMA groups in isolation, or in the Type II+III group combined, when subjects with maximum or minimum MHFMS scores were removed (data not shown) (21 subjects with a minimum score, and 42 subjects –22 with SMA and 20 control – with a maximum score). The gene discussed is SMN2; the disease is proximal spinal muscular atrophy.