We examined the effects of high- versus low-anxious behavioral phenotypes on mean levels of gene expression of critical chemokines and cytokines that are known to have important protective (cutaneous T cell attracting chemokine (CTACK also known as CCL27), interleukin (IL)-12, interferon gamma (IFN-γ)) versus tumor-promoting (CCL22, IL-10, IL-4) effects in the context of SCC [25], [51]. The gene discussed is CCL27; the disease is neoplasm.