There are major differences between 1) inflammatory cells within cancer cell nests in carcinomas (epithelial CD57 positive cells); 2) inflammatory cells present in the stroma of epithelial tumors (stromal CD57 positive cells), 3) inflammatory cells present along the invasive margins (peritumoral CD57 positive cells); and, 4) inflammatory cells in the peritumoral capsule of stromal tumors such as STS. The gene discussed is B3GAT1; the disease is telomere syndrome.