ANGPT1 and infection: To address this hypothesis, cytokine, chemokine, and expression of the endothelial activation marker angiopoietin-1/2 (Ang-1/2) was quantified based on CB and FB status, gender, age group, country of travel, and species of Plasmodium (P. vivax, P. falciparum, Plasmodium malariae and Plasmodium ovale) infection.