One interpretation of these results is that the MYOC protein plays a particularly important role in the globe and that regulation of MYOC expression that might be pertinent to POAG, congenital glaucoma, and/or steroid-induced glaucoma is relatively specific to the TM and may not be reflected to a significant extent in bone marrow or other non-ocular tissues. This evidence concerns the gene MYOC and open-angle glaucoma.