Furthermore, we investigated the correlations between MVD or p53 status and other assessed previously clinicopathological variables including tumor clinical stage, grade, estrogen (ER) and progesterone (PgR) receptors, HER2, cytokeratin 5/6 (CK5/6) status as well as TOPOIIα expression and proliferation rate. The gene discussed is TP53; the disease is neoplasm.