NOS3 and myocardial infarction: Recent studies also have shown that Salvianolic acid B (Sal B) and Tanshinone IIA (Tan IIA) are two of the major components in Danshen, have cardioprotective effects in an in vivo myocardial infarction model of C57 mice, have vasodilator action in an ex vivo microartery system through the endothelial nitric oxide synthase (eNOS)/nitric oxide pathway, and are involved in the regulation of the L-arginine/eNOS/NO pathways in human umbilical vein endothelial cells (HUVECs).