Others tumor metastasis genes — Caveolin-1 (CAV1), H-Cadherin (CDH13), EPHA7, and S100A2 are often downregulated in prostate tumor tissues when compared to adjacent normal tissues due to methylation [47, 74, 76, 81, 85, 92, 127-134]. The gene discussed is CAV1; the disease is neoplasm.