However, and following the significant reduction of haemoglobin (Hb) observed in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency after treatment with CD and artesunate (CDA) in two phase III trials [1,5], clinical research on this product was stopped and all CD doses already on the market withdrawn [6]. The gene discussed is GSTM1; the disease is G6PD deficiency.