CD4 and cardiomyopathy: Interestingly, the inhibitory activity of CD4+CD25+ T cells from healthy individuals (62.95±5.37) (P = 0.0159) and free/mild cardiomyopathy patients (57.40±9.18) (P = 0.0189) were significantly higher than that observed with CD4+CD25+ T cells from moderate/severe cardiomyopathy patients (33.76±4.67), when cultured at a ratio of 1∶5 Treg∶allogeneic T cell (Figure 4B).