RHO and retinal degeneration: A similar process in which retinal vessels are located adjacent to Bruch's membrane and are covered by RPE cells has been described in late stage retinal degeneration in rhodopsin knockout mice [55] suggesting that the development of this type of RPE/vascular lesions may be not only specific to retinal degeneration caused by mutations in Crb1, but might be more common during late stages of other severe retinal degenerations.