CX3CL1 and retinal detachment: This hypothesis is consistent with the increased expression of Cx3cl1 in retinal and choroidal vascular endothelial cells, Müller cells, RPE as well as photoreceptors after inflammatory processes [56] as well as with the observed upregulation of Ccl2 in Müller cells within affected retinal areas after focal light injury and after retinal detachment [57], [58].