CD4 and infection: Co-culturing mDCs that had been exposed to an equivalent amount of infectious HIVNL4-3 derived from NB-DNJ-treated or untreated CD4+ T cells with the TZM-bl reporter cell line revealed a strong reduction of trans-infection for the virus from inhibitor-treated cells compared to control virus (p = 0.0404, paired t test) (Figure 6D).