Recently, an in vitro study has demonstrated that L-733,060, combined with vinblastine or microtubule perturbing agents, is synergistic for the growth inhibition of the NK-1 receptor-possessing cancer cell lines (T98G, U87, Hela, T24, and MDA-MB-231), but not for normal lung IMR-90 fibroblast cells. This evidence concerns the gene TACR1 and cancer.