IL10 and Parkinson disease: We have found using an in vitro model of PD that the addition of IL-10 to a mixed glial cell-neuron cell culture abrogated the degeneration of the neuron cells induced by either LPS or MPTP [60], and this inhibitory effect was mediated through its inhibition of the production of extracellular superoxide in the microglia cells within the mixed cell culture [105].