IGHE and asthma: However, the combination of positive MDI-SIC, MDI-SPT and specific IgE antibodies correlated with asthma diagnosis (with RR of 5.7, P < 0.001, n = 12), whereas MDI-HSA-specific IgE alone showed RR of 1.28, P < 0.50 (when correlated with the clinical OAI diagnosis) given the limitation of the small patient group.