So to understand the interplay between the disease healing inflammatory cytokines, IFN-γ and IL-12 as well as disease associated cytokines, IL-10 and IL-4, we sought to investigate the expression of these cytokines and the level of iNOS transcript, which play major role in leishmaniasis control, in infected control as well as vaccinated groups by qRT-PCR. This evidence concerns the gene IFNG and leishmaniasis.