SNCA and Parkinson disease: Postmortem analysis and quantification of catecholaminergic cell and terminal loss in susceptible tissues, as well as evaluation of pathologies typical of PD–related neurodegeneration, such as inflammatory cell response and intracytoplasmic accumulation of alpha synuclein [56], are warranted to further characterize the effect of 6-OHDA in peripheral catecholaminergic cells.