Since we observed that primary MSCs (both from normal donors and myeloma patients) are more sensitive to this effect of dasatinib than the hMSC-TERT cell line, it is worth to mention that if dasatinib is used in the clinical setting to pursue an osteogenic effect, special precaution should be taken to achieve a compromise within reduced osteoprogenitor cell numbers and enhanced osteogenic differentiation. Here, TERT is linked to plasma cell myeloma.