NKX6-1 and familial pancreatic carcinoma: Also of interest are homeobox protein NKX6.1 for MODY (Donelan et al. 2010); protein S and platelet-derived growth factor BB for acute kidney injury (Thurman et al. 2009); WNT target-gene promoter TBL1XR1 (F-box-like/WD repeat containing protein) for acute lymphoblastic leukemia (Parker et al. 2008); and proto-oncogene serine/threonine-protein kinase PIM1, which is proposed as a marker for mutated K-ras signaling activity in pancreatic cancer (Xu et al. 2011).