The interplay of the NGF and the VEGF-C could also be investigated and the expansion of knowledge in the synergistic interplay pathway of the NGF and VEGF-C in the angiogenic pathogenesis of psoriasis vulgaris would prove useful for the development of future therapeutic agent against the signaling cascades mediated by the NGF and VEGF-C. Here, VEGFC is linked to psoriasis vulgaris.