For instance, a genome-wide association study (GWAS) evaluating 317,501 single nucleotide polymorphisms (SNPs) in 720 women of European ancestry with SLE and 2,337 controls disclosed four loci associated with the disease harboring the following genes: ITGAM, KIAA1542, PXK, and the SNP rs10798269 in chromosome 1q25.1 [23]. Here, ITGAM is linked to systemic lupus erythematosus.