Although several studies have suggested a role for the mGSTP1 promoter as a biomarker for HCC detection, to our knowledge, the methylation status of the GSTP1 promoter has not been analyzed by bisulfite sequencing, which is used to analyze every CpG site in the region examined, across the spectrum of normal liver, hepatitis, cirrhosis, and HCC. Here, GSTP1 is linked to hepatocellular carcinoma.