In order to confirm if cytosolic persistence of the recombinant L.inn::vgc strain is efficient enough to stimulate production of such cytokines, we examined the transcriptional responses of IFN-a2 and IFN-b1 in bone marrow-derived macrophages following infection with Lm, L.inn as well as the recombinant L.inn::vgc strain. This evidence concerns the gene IFNA2 and infection.