However, in some other studies, the same CX3CR1 deficiency conversely led to microglia accumulation in the ONL and subsequent neuronal degeneration and neovascularization in an AMD model [65], as well as in experimental autoimmune uveitis, resulting in a significant increase in neuron apoptosis and prolonged inflammatory response [66]. This evidence concerns the gene CX3CR1 and autoimmune uveitis.