Compared to the heat pattern versus control analysis, the cold pattern versus control analysis revealed that different pathways were related to the following differentially expressed genes (Table 5): glycosylphosphatidylinositol (GPI) anchor biosynthesis, arachidonic acid metabolism, Jak-STAT signaling, hematopoietic cell lineage, primary immunodeficiency, cytokine-cytokine receptor interactions, ABC transporters, pentose and glucuronate interconversions, and axon guidance. Here, ABCG2 is linked to inborn error of immunity.