In this sense, we have recently reported that DDD, DDE, aldrin, and dieldrin, sharply upregulated the expression of a number of protein kinases genes that could be involved in the etiology of BC, such as ACVRL1, ALK-1, KIT, ERBB3, and ALK-1, at concentrations close to those detected in human populations [34]. The gene discussed is ACVRL1; the disease is breast cancer.