Dendooven et al. [36] reported that plasma CTGF was increased in type 1 diabetes subjects with kidney disease, compared to those with normoalbuminuria, but there were no significant associations of the −945 G/C polymorphism with plasma CTGF levels or cardiovascular mortality, non-fatal cardiovascular events and end-stage kidney disease. Here, CCN2 is linked to type 1 diabetes mellitus.