The lack of association of individual UCP2 SNPs and disease traits in the Balinese population might be due to the influence of other genetic or environmental factors that were not studied in this research, such as the MTNR1B gene polymorphism that has been reported to be associated with type 2 diabetes mellitus and lipid levels in Han Chinese population [52]. This evidence concerns the gene MTNR1B and type 2 diabetes mellitus.