Importantly, when naïve cd8−/− mice were reconstituted with CD8+ cells from ifnγ+/+pfn−/− naïve donors (deficient in Pfn but able to express IFNγ), after infection these animals exhibited less severe myocardial cell lesion and a more preserved electrical conduction, with a low incidence of AVB2 and a more normal heart rate. Here, CD8A is linked to infection.