LGR5 and adenocarcinoma: LGR5-mRNA was significantly differentially expressed in adenocarcinomas of the oesophagus (p = 0.007), stomach [intestinal type (p = 0.006) and diffuse type (p = 0.013)], liver [CCs (p = 0.022)], colon (p<0.001) as well as rectum (p = 0.002) compared with the matched non-neoplastic tissue.