ESR1 and neoplasm: The following variables were found significantly correlated to the following combinations of Histological Grade and of Genomic Grade [HG-1_GG-1/HG-2_GG-1/HG-2_GG-3/HG-3_GG-3]: histological type, tumor size, vascular invasion, mitotic index, Ki67 score, ER and PR status, triple negative status, metastatic events.