CEMIP and carcinoma: This gene of uncertain function has previously been reported to be strongly up-regulated in colorectal adenomas (n = 32) and carcinomas (n = 25) analyzed in a study by Sabates-Bellver et al. The study also show that the expression of 19 Wnt targets was closely correlated with up-regulation of KIAA1199, and that the expression in normal mucosa was limited to cells in the lower portion of colonic crypts [53], [54].