Interestingly, similar results were also observed in other human cancers, such as Straughn JM et al reported that CgA stained positive carried a significantly worse prognosis in patients with SCCC; tumors from the long-term survivors stained negative for CgA; patients with CgA -positive tumors were 21 times more likely to die (RR = 21.00) than patients negative for CgA (95% CI, 1.88–233.00). The gene discussed is CGA; the disease is cancer.