CD40LG and tuberculosis: Imaz et al. in 2001 [25] reported the usefulness of the recombinant 16-kDa antigen (re-Ag16) of Mycobacterium tuberculosis in the serodiagnosis of tuberculosis (TB) in children measuring the values of IgA, IgM, and IgG and an increased mean antibody response to reAg16 was observed in contact children compared with nonmycobacterial disease patient with a 95% of specificity.