IL10 and chlamydia trachomatis infectious disease: For example, using the murine model of C. trachomatis MoPn lung infection, IL-10 inhibits host clearance of chlamydial infection in the susceptible BALB/C mouse strain (which produces more IL-10) and negatively regulates inflammatory responses in the resistant C57BL/6 mouse (which produces less IL-10) [23].