Numerous reports demonstrate that basal levels of HspA1A, both in a serum and in a tumor microenvironment of patients with various cancers (breast, lung, prostate, colorectal, pancreatic), often correlate with poor survival and response to chemotherapy of patients (Abe et al. 2004; Suzuki et al. 2006; Zhang et al. 2009; Sherman and Multhoff 2007; Aghdassi et al. 2007). Here, HSPA1A is linked to cancer.