HSPA1A and neoplasm: The environment surrounding cancer cells is deficient in oxygen, nutrients, and glucose but is enriched in pro-inflammatory cytokines and cytotoxic agents that enhance the basal level of HspA1A in tumor cells and which, on the other hand, is essential to the growth and survival of cancer cells (Weber and Kuo 2011; Wilson and Balkwill 2002; Daugaard et al. 2005).