Genes encoding MHC molecules such as H2-Ab1 (FC −2.32) and H2-Eb1 (FC −2.36), which have been implicated in atherosclerosis [62], were down-regulated in the spleens of mice, thus suggesting that OPP was able to attenuate the inflammatory response brought about by the atherogenic diet. Here, H2AB1 is linked to atherosclerosis.