Thus, using a multigene signature covering one particular disease-associated module with AID as the key gene, we further explored associations between AID and other molecules involved in the etiology of human inflammation-driven disease such as nasal polyposis: in addition to the previously highlighted biomarkers/targets such as IgE and IL5, novel players were suggested including among others IL13 and CD23 [21]. This evidence concerns the gene AICDA and Nasal polyposis.