CD40LG and autoimmune polyendocrinopathy: Regarding test items of aPLs for RSA, an international consensus statement concerning the update of the classification criteria for definite antiphospholipid syndrome (APS), published in February 2006 [5], specified only anticardiolipin antibody (aCL) of IgG and/or IgM isotype in a medium or high titer (over the 99th percentile), anticardiolipin-β2 glycoprotein-I antibody (aβ2GPI) of IgG and/or IgM isotype (over the 99th percentile), and lupus anticoagulant (LA).