Figure 1B shows that the mean concentrations of IL-12 in the right hemisphere of the rAAV2/IL12 treated rats with no tumor implantation [AAV2/IL12 R(no) group] were increased from 3.4 ± 2.1 pg/mg prior to the injection to a maximum of 70.2 ± 12.3 pg/mg on the last day of week 4, but declined to 34.2 ± 19.3 pg/mg on the last day of week 8; the mean concentrations of IL-12 in the left hemisphere of the same rats [AAV2/IL12 L(no) group] were below 13 pg/mg at all time points. Here, IL12RB1 is linked to neoplasm.