Figure 1A shows that the mean levels of IFN-γ in the right hemisphere of the rAAV2/IL12 treated rats with no tumor transplantation [rAAV/12 R (no) group] was increased from 33.5 ± 2.2 pg/mg prior to the injection to the maximum of 143.4 ± 15.5 pg/mg on the last day of week-6, and declined to 67.5 ± 21.7 pg/mg on the last day of week-8; in the left hemisphere, the mean concentrations of IFN-γ were increased from 31.2 ± 1.8 pg/mg prior to injection to the maximum of 88.2 ± 1.8 pg/mg on the last day of week-6, and declined to 40.0 ± 9.1 pg/mg on the last day of week-8. This evidence concerns the gene IFNG and neoplasm.