EDA and neoplasm: We demonstrated that expressions of ED1 and TRAIL were ipsilaterally abundant in the tumor tissue of rAAV2/IL12-treated rats (Figure 3A), but less in that of PBS-treated rats (Figure 3B), indicating that the rAAV2/IL12 transfection can enhance more infiltration of activated microglias that secrete ED1 and TRAIL in the transplanted tumor.