ACE2 and hydrops fetalis: In contrast, the SVF isolated from visceral (RPF) adipose tissue, but not gonadal (EF) or subcutaneous (SubQ) adipose tissue of HF-fed mice, exhibited significantly increased ACE2 activity compared to LF-fed controls (Figure 1; P < 0.05 for RPF; P = 0.06 for EF; P > 0.05 for SubQ).